5 Amino 1MQ

5‑Amino‑1‑Methylquinolinium (5‑Amino‑1MQ) is a synthetic quaternary ammonium analogue of naturally occurring methylquinolinium, designed to selectively inhibit cytosolic nicotinamide N‑methyltransferase (NNMT). NNMT catalyzes the transfer of a methyl group from S‑adenosyl‑L‑methionine (SAM) to nicotinamide and related substrates; by competing with nicotinamide for NNMT binding, 5‑Amino‑1MQ elevates intracellular NAD⁺ levels and alters methylation flux, making it a key reagent for studies of methyltransferase regulation and cellular energy homeostasis.

Note: 5 Amino 1MQ is intended for research purposes only and is not approved for human consumption. All products are shipped in lyophilized form and must be reconstituted to a liquid for research and testing. We are unable to provide any dosing instructions. All products should be considered pharmaceutical grade.