Semax is a synthetic heptapeptide analog of ACTH(4‑10) notable for its exceptional stability and brain‑targeting properties. In laboratory investigations, it has attracted interest as a neurotrophic and neuroprotective signaling agent: Semax resists degradation by peptidases, enabling it to penetrate the blood–brain barrier and engage melanocortin receptors. There, it upregulates BDNF and NGF expression, enhances cerebral microcirculation, and modulates monoaminergic neurotransmission to support synaptic plasticity, cognitive resilience, and neuronal survival under stress or ischemic challenge. Its unique combination of stability, receptor‑mediated action, and multifaceted support of neurotrophic pathways makes it an invaluable tool for researchers modeling neurodegeneration, cognitive fatigue, and recovery from brain injury.
Note: Semax is intended for research purposes only and is not approved for human consumption. All products are shipped in lyophilized form and must be reconstituted to a liquid for research and testing. We are unable to provide any dosing instructions. All products should be considered pharmaceutical grade.
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